Dog Heartworm Preventive Products Comparison Chart
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Heartworm Preventive Comparison Chart

Drs. Foster & Smith Educational Staff
Click here for a pdf version of this article.

Medications used to prevent heartworm infections are called preventives. Preventives kill the heartworm larvae before they have a chance to grow and mature into adult heartworms. A number

of heartworm preventives are available to pet owners today. Some heartworm preventives contain additional ingredients that will control other parasites, such as roundworms or hookworms. A monthly preventive should be given to all pets. Remember that mosquitoes can get indoors, so even though your pet may not go outside, he is still susceptible.

Product Minimum Age/Weight Dose Given Active Ingredient Against Heartworm Additional Ingredients Also Effective Against
Heartgard® Plus for Dogs 6 wks Monthly; oral Ivermectin Pyrantel pamoate Roundworms and hookworms
Heartgard® for Cats 6 wks Monthly; oral Ivermectin None Hookworms
Tri-Heart® Plus for Dogs 6 wks Monthly; oral Ivermectin Pyrantel pamoate Roundworms and hookworms
Iverhart Max® for Dogs 8 wks Monthly; oral Ivermectin Pyrantelpamote,Praziquantel Roundworms, hookworms, and tapeworms.
Sentinel® for Dogs 4 wks and2 lbs Monthly; oral Milbemycin oxime Lufenuron Roundworms, whipworms, some hookworms, and flea eggs.
Revolution® for Dogs 6 wks Monthly; topical Selamectin None Fleas, flea eggs, ear mites, sarcoptes mange, and American Dog Ticks.
Revolution® for Cats 8 wks Monthly; topical Selamectin None Fleas, flea eggs, ear mites, one type of hookworm and one type of roundworm.
Advantage Multi™ for Dogs 7 wks and 3 lbs Monthly; topical Moxidectin Imidacloprid Fleas, roundworms, hookworms, and whipworms.
Advantage Multi™ for Cats 9 wks and 2 lbs Monthly; topical Moxidectin Imidacloprid Fleas, roundworms, hookworms, and ear mites.
Trifexis 8 wks and 5 lbs Monthly; chewable Milbemycin oxime and Spinosad N/A Fleas, roundworms, hookworms, and whipworms.

Learn what every pet owner needs to know about heartworm prevention: visit our Special Heartworm Disease Information Section!

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